Development of <i>in-silico</i> drug cardiac toxicity evaluation system with consideration of inter-individual variability-Reference-Cited by-同舟云学术

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Development of in-silico drug cardiac toxicity evaluation system with consideration of inter-individual variability

Published:2024 Issue:2 Volume:32 Page:83
ISSN:2289-0882
Container-title:Translational and Clinical Pharmacology
language:en
Short-container-title:Transl Clin Pharmacol

Author:

Qauli Ali Ikhsanul¹²^ORCID,Danadibrata Rakha Zharfarizqi¹^ORCID,Marcellinus Aroli¹^ORCID,Lim Ki Moo¹³⁴^ORCID

Affiliation:

1. Department of IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Korea.

2. Department of Engineering, Faculty of Advanced Technology and Multidiscipline, Universitas Airlangga, Surabaya 60115, Indonesia.

3. Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39177, Korea.

4. Meta Heart Inc., Gumi 39177, Korea.

Funder

Ministry of Food and Drug Safety

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Publisher

XMLink

Link

https://tcpharm.org/pdf/10.12793/tcp.2024.32.e7

Reference32 articles.

1. Preclinical Torsades-de-Pointes Screens: Advantages and limitations of surrogate and direct approaches in evaluating proarrhythmic risk

2. Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium

3. Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk

4. Uncertainty Quantification Reveals the Importance of Data Variability and Experimental Design Considerations for in Silico Proarrhythmia Risk Assessment

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