Therapeutic efficacy of an interferon inducer in the treatment and prophylaxis of acute respiratory viral infections in childhood: A review-Reference-Cited by-同舟云学术

Therapeutic efficacy of an interferon inducer in the treatment and prophylaxis of acute respiratory viral infections in childhood: A review

Published:2023-10-04 Issue:3 Volume: Page:164-172
ISSN:2658-6622
Container-title:Pediatrics. Consilium Medicum
language:
Short-container-title:Pediatr. Con. Med.

Author:

Mizernitskiy Yury L.^ORCID,Dorovskaya Nelly L.^ORCID,Melnikova Irina M.^ORCID

Abstract

The high incidence of acute respiratory viral infections (ARVI), including influenza, warrants the need for effective and safe methods of ARVI treatment and prevention. Due to the limited options for specific prevention of highly pathogenic and highly virulent viral infections (influenza, SARS-CoV-2), the non-specific prevention and complex therapy of influenza and other ARVI are relevant. Immunostimulating agents with a dual mechanism of action, including endogenous interferon (IFN) inducers, have both antiviral and immunocorrective effects. A detailed review of recent literature on the prophylactic and therapeutic efficacy of the IFN inducer Kagocel is presented, as well as the authors' own experience. A significant evidence pool allows the use of the drug to treat and prevent acute respiratory viral infections and influenza in children from 3 years of age.

Publisher

Consilium Medicum

Reference54 articles.

1. Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека. О состоянии санитарно-эпидемиологического благополучия населения в Российской Федерации в 2021 году: Государственный доклад. 2022 [Federal'naia sluzhba po nadzoru v sfere zashchity prav potrebitelei i blagopoluchiia cheloveka. O sostoianii sanitarno-epidemiologicheskogo blagopoluchiia naseleniia v Rossiiskoi Federatsii v 2021 godu: Gosudarstvennyi doklad. 2022 (in Russian)].

2. Геппе Н.А., Козлова Л.В., Горелов А.В., и др. Острые инфекции дыхательных путей у детей. Диагностика, лечение, профилактика. Клиническое руководство, 2-е изд. М.: МедКом-Про, 2020 [Geppe NA, Kozlova LV, Gorelov AV, et al. Ostrye infektsii dykhatel'nykh putei u detei. Diagnostika, lechenie, profilaktika. Klinicheskoe rukovodstvo, 2-e izd. Moscow: MedKom-Pro, 2020 (in Russian)].

3. Antiviral therapy of acute respiratory viral infection and influenza in children in a hospital

4. Ющук Н.Д., Хадарцев О.С. Использование интерферонов в профилактике и лечении респираторных вирусных инфекций у взрослых и детей. Лечащий врач. 2018;3:67-72 [Iushchuk ND, Khadartsev OS. Use of interferon in prevention and treatment of respiratory viral infections in adults and children. Lechashchii vrach. 2018;3:67-72 (in Russian)].