Affiliation:
1. Center for Theoretical Problems of Physico-Chemical Pharmacology of the Russian Academy of Sciences
2. LLC “Scientific and Clinical Consulting Center of Allergology and Immunology”
3. Sechenov First Moscow State Medical University (Sechenov University)
4. Mechnikov Research Institute of Vaccines and Sera
Abstract
Обоснование. Atopic dermatitis (AD) is one of the most common skin disorders in pediatric practice. In AD, the barrier function of the skin and moisturizing factors are impaired, which requires using specialized care products. Therefore, healthcare professionals should be aware of effective and safe products that can be used in children.
Aim. To evaluate the clinical efficacy of LA-KRY cosmetics.
Materials and methods. The study included 39 patients with AD and 26 patients with allergic/contact dermatitis aged 0-7 years. In some children, skin corneometric indices (SCI) (humidity and oiliness) were measured before using care products and 14 and 30 days after the start of their use to assess their effectiveness. In the remaining patients, the clinical manifestations of skin disorders were assessed visually without instrumental methods.
Results. SCI improvement was observed after 14 days of using LA-KRY products and significantly improved by the end of month 1. Minimization of dryness and itching of the skin occurred by days 3-5, and clinical manifestations resolved by days 14-30 (depending on the nosology).
Conclusion. LA-KRY have shown their effectiveness in children with several dermatoses associated with skin barrier disruption, dryness, and itching; in particular, they help reduce inflammation and discomfort and normalize SCI.