Author:
Gorelov Aleksandr V.,Zakharova Irina N.,Khavkin Anatolii I.,Kafarskaya Liudmila I.,Usenko Denis V.,Belmer Sergei V.,Kornienko Elena A.,Privorotsky Valerii F.,Krasnov Viktor V.,Kondyurina Elena G.,Panfilova Viktoriia N.,Tkhakushinova Nafiset Kh.,Plaksina Anna N.,Rychkova Olga A.,Pechkurov Dmitrii V.,Nizhevich Aleksandr A.,Fayzullina Rezeda A.,Yablokova Ekaterina A.
Abstract
The appearance of new high-tech microbiological research methods has significantly changed the understanding of the human microbiome. The purpose of the meeting of the Council of Experts Dysbiosis. The immediate and long-term consequences of microbiome disorders and options for their correction with probiotics was the definition of modern positions about possible methods of studying the intestinal microbiome, the possibilities of correcting dysbiosis, the use of Saccharomyces boulardii CNCM I-745 to correct microbiome disorders in various clinical situations. The criteria of the microbiological norm for the intestinal microbiome have not been definitively established. To study the microbiome, a set of methods is used that combine cultural and molecular genetic methods that complement each other. Currently, there are no clinical markers of dysbiosis, and laboratory markers of dysbiosis require modification.
Probiotics can provide restoration of the intestinal microbiota. The effectiveness and safety of the use of Saccharomyces boulardii CNCM I-745 for this purpose has been proven. In the case of acute intestinal infection, antibiotic-associated diarrhea, and the consequences of HP infection eradication, studies have a high level of evidence.
This article is a reprint. Primary Publication: Gorelov AV, Zakharova IN, Khavkin AI, Kafarskaya LI, Usenko DV, Belmer SV, Kornienko EA, Privorotsky VF, Krasnov VV, Kondyurina EG, Panfilova VN, Tkhakushinova NKh, Plaksina AN, Rychkova OA, Pechkurov DV, Nizhevich AA, Fayzullina RA, Yablokova EA. Resolution of the Council of Experts Dysbiosis. Immediate and long-term consequences of microbiome disorders and options for their correction with probiotics. Vopr. prakt. pediatr. (Clinical Practice in Pediatrics). 2022;17(1):213221 (in Russian). DOI: 10.20953/1817-7646-2022-1-213-221. With the permission of the copyright holder. Published with reductions.