Visceral leishmaniasis: a challenging diagnosis in internal medicine

Author:

Brovko M. Iu.ORCID,Akulkina L. A.ORCID,Potapov P. P.ORCID,Sholomova V. I.ORCID,Lebedeva M. V.,Nekrasova T. P.ORCID,Varshavskii V. A.,Volchkova E. V.,Rozina T. P.ORCID,Nikulkina E. N.ORCID,Karan L. S.ORCID,Moiseev S. V.ORCID,Fomin V. V.ORCID

Abstract

Leishmaniasis is a vector-born parasitic disease characterized by predominant cutaneous or visceral involvement with fever, hepatosplenomegaly and anemia. Leishmaniasis has relatively high prevalence in tropical and subtropical areas. Several sporadic and mostly imported cases are detected in Russian Federation. Nevertheless, some local incidents are noted in southern areas (Crimea, Dagestan). Lack of epidemiological alertness hampers confirmation of diagnosis and may lead to incorrect treatment. The article summarizes current state of knowledge in epidemiology, diagnostic approach and treatment of leishmaniasis. Particular clinical case is discussed.

Publisher

Consilium Medicum

Subject

General Medicine,Endocrinology, Diabetes and Metabolism,History,Family Practice

Reference18 articles.

1. World Health Organization, Working to overcome the global impact of neglected tropical diseases: First WHO Report on neglected tropical diseases (Geneva: World Health Organization 2010). Accessed 7 Oct 2018.

2. Torres-Guerrero E, Quintanilla-Cedillo MR, Ruiz-Esmenjaud J, et al. Leishmaniasis: a review. F1000 Res. 2017;6:750.

3. WHO. Epidemiological situation. WHO – 2018.

4. Clinical and epidemiological features of visceral leishmaniasis in the Republic of Crimea

5. Diagnosis and Treatment of Leishmaniasis: Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH)

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