NSAID enteropathy-Reference-Cited by-同舟云学术

NSAID enteropathy

Published:2020-02-27 Issue:2 Volume:92 Page:85-92
ISSN:2309-5342
Container-title:Terapevticheskii arkhiv
language:
Short-container-title:Terapevticheskii arkhiv

Author:

Kareva E. N.

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used drugs in the world, and their side effects are very high. First of all, these are NSAID gastropathy, but in the long term, 5070% of NSAIDs cause damage to the small intestine (NSAID enteropathy), sometimes with serious consequences. To date, no drugs have been proposed with proven effectiveness to prevent this side effect. Apparently, this is not due to the fully clarified mechanism of pathogenesis. The most promising is the hypothesis of the participation of individual representatives of microflora in the development of enteropathy. Therefore, modulating the intestinal flora with the help of probiotics can be the basic therapeutic strategy for the prevention and treatment of such damage.

Publisher

Consilium Medicum

Subject

General Medicine,Endocrinology, Diabetes and Metabolism,History,Family Practice

Link

https://ter-arkhiv.ru/0040-3660/article/viewFile/33914/pdf

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