History of the discovery and study of tick-borne encephalitis in Russia: three Far Eastern expeditions (1937

History of the discovery and study of tick-borne encephalitis in Russia: three Far Eastern expeditions (1937–1939)

Published:2021-11-15 Issue:11 Volume:93 Page:1407-1412
ISSN:2309-5342
Container-title:Terapevticheskii arkhiv
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Short-container-title:Terapevticheskii arkhiv

Author:

Kolyasnikova Nadezhda M.^ORCID,Zlobin Vladimir I.^ORCID,Ishmukhametov Aidar A.^ORCID,Maleev Viktor V.^ORCID

Abstract

The review provides a brief historical outline of the discovery and study of tick-borne encephalitis (TBE) during three expeditions to the Far East (19371939). As a result of the Far Eastern expeditions, the TBE virus was discovered, numerous strains were isolated, a vector-borne transmission pathway was established, the main features of epidemiology, clinic and pathomorphology of the disease were described, serotherapy was tested, first inactivated "brain" vaccine against TBE was developed and its effectiveness was proved. The history of the discovery and study of TBE is marked by the heroism of researchers and tragic events illness of some participants, death during the development of the first vaccine, arrest of L.A. Zilber and two performers.

Publisher

Consilium Medicum

Subject

General Medicine,Endocrinology, Diabetes and Metabolism,History,Family Practice

Link

https://ter-arkhiv.ru/0040-3660/article/viewFile/99734/pdf

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