Affiliation:
1. Department of Anesthesiology and Perioperative Medicine
2. Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Abstract
Differential diagnosis of the underlying cause of new-onset total body paralysis can be challenging and unsatisfying. In akinetic mutism, a rare side effect of tacrolimus, patients become apathetic, mute, and lose voluntary muscle movement. Epidural subarachnoid migration can present with similar symptoms. Delayed emergence/paralysis after anesthesia can include the common culprits of residual operative medications, stroke, as well as tacrolimus-induced akinetic mutism and thoracic epidural migration. We present a case of new-onset total body paralysis, presenting on postoperative day 1 following a double-lung transplant in a patient started on tacrolimus with a thoracic epidural catheter in place.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Cited by
1 articles.
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1. Tacrolimus;Reactions Weekly;2023-09-02