Affiliation:
1. Helmholtz National Medical Research Center of Eye Diseases
Abstract
In the first part of the review [ROJ, 2023; 16 (2): 160–2], we discussed the common and specific features of adaptive and non-adaptive retinal plasticity characteristic of glaucoma, age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy, and retinopathy of prematurity. The presented part of the review discusses the issues of axon regeneration of retinal ganglion cells and analyzes therapeutic approaches aimed at maximizing the plasticity and stimulating the reparative potential of the retina. The protective effects of "conditioning" stimuli in the modifying treatment of retinal diseases are considered. Some of the present-day visual rehabilitation strategies based on visual perception training and visual fixation training using biofeedback systems are reported.
Reference67 articles.
1. Crair MC, Mason CA. Reconnecting eye to brain. J Neurosci. 2016; 36 (42): 10707–22. doi: 10.1523/JNEUROSCI.1711-16.2016
2. Sauv Y, Gaillard F. Regeneration in the visual system of adult mammals. Webvision: The Organization of the Retina and Visual System [Internet. Salt Lake City (UT): University of Utah Health Sciences Center; 1995 [updated 2007 Jun 21. PMID: 21413374
3. Chen DF, Jhaveri S, Schneider GE. Intrinsic changes in developing retinal neurons result in regenerative failure of their axons. Proc Natl Acad Sci USA. 1995; 92 (16): 7287–91. doi: 10.1073/pnas.92.16.7287
4. Vidal-Sanz M, Bray GM, Villegas-Perez MP, Thanos S, Aguayo AJ. Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J Neurosci. 1987; 7: 2894–909. doi: 10.1523/JNEUROSCI.07-09-02894.1987
5. Aguayo AJ, Rasminsky M, Bray GM, et al. Degenerative and regenerative responses of injured neurons in the central nervous system of adult mammals. Philos Trans R Soc Lond B Biol Sci. 1991; 331: 337–43. doi: 10.1098/rstb.1991.0025
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献