Adverse effects of prostaglandin analogues used in ophthalmological practice

Author:

Kazanova S. Yu.1

Affiliation:

1. Central City Hospital

Abstract

Prostaglandin analogues are a class of antihypertensive drugs for glaucoma treatment which are systematically safe but have a sufficiently large number of local side effects. These effects may worsen the quality of life of patients with glaucoma and reducetheir adherence to treatment routines due to physical and psychological discomfort. The review presents literature data and clinical cases fromthe author’s own medical practice.

Publisher

Real Time, Ltd.

Subject

Ophthalmology

Reference52 articles.

1. European Glaucoma Society. Terminology and guidelines for glaucoma. 4th ed. Savona: Italy PubliComm; 2014.

2. Egorov E.A., Erichev V.P.Medicamental antihypertensive treatment of glaucoma. In: Egorov E.A., ed. Glauсoma. Nacional Guidelines. Moscow: GEOTAR-Media; 2013: 427–67 (in Russian)].

3. Weinreb R.N., Kashiwagi K., Kashiwagi F., Tsukahara S., Lindsey J.D. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells. Invest. Ophthalmol. Vis. Sci. 1997; 38 (13): 2772–80.

4. Sharif N.A., Kelly C.R., Crider J.Y. Agonist activity of bimatoprost, travoprost, latanoprost, unoprostone isopropyl ester and ot her prostaglandin analogs at the cloned human ciliary body FP prostaglandin receptor. J. Ocul. Pharmacol. Ther. 2002; 18 (4): 313–24. doi: 10.1089/10807680260218489

5. Sharif N.A., Kelly C.R., Crider J.Y. Human trabecular meshwork cell responses induced by bimatoprost, travoprost, unoprostone, and other FP prostaglandin receptor agonist analogues. Invest. Ophthalmol. Vis. Sci. 2003; 44 (2): 715–21. doi: 10.1167/iovs.02-0323

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