Using of modern types of drainage in glaucoma surgery: our experience

Author:

Gavrilova T. V.1,Lyubimov K. S.1,Mukhamadeeva S. N.2,Chereshneva M. V.3

Affiliation:

1. E.A. Wagner Perm State Medical University; Perm Regional Clinical Hospital

2. Perm Regional Clinical Hospital

3. Institute of Immunology and Physiology, Ural Branch, Russian Academy of Sciences

Abstract

Purpose. To evaluate antihypertensive efficiency and safeness of Xenoplast, Glautex, and Ex-PRESS drainage during glaucoma surgery. Material and methods. 249 patients with primary open angle glaucoma (253 eyes) underwent antihypertensive operations with Xenoplast (group I, 121 patients aged 68.6 ± 7.7 yrs), Glautex (group II, 49 patients aged 66.8 ± 7.7 yrs) and Ex-PRESS (group III, 79 patients aged 67.9 ± 8.3 yrs). In groups I and II, drainages were implanted during penetrating and non-penetrating surgery. Long-term results were traced for 2 years. Results. In the early postoperative period, all groups had complications typical for antiglaucoma surgery without drainage: I — 14.8 %, II — 16.8 %, III — 16.8 %. An absolute success of the operation (normalization of IOP without additional antihypertensive therapy) was achieved as follows. In group I for patients with non-penetrating deep sclerectomy it was achieved in 98.4 % of cases at the moment of discharge from hospital, whereupon the figure fell to 15.4 % in 18 months. In group I patients, with trabeculectomy the success was achieved in 96.7 %, dropping to 6.7 %. In group II for patients with non-penetrating deep sclerectomy the success claimed 96.3 %, but after 12 months it vanished completely. In group II with trabeculectomy the success reached 95.7 %, but dropped to 16.7 % after 24 months. In group III the success rate at the moment of discharge was 96.3 % but it dropped to 16.7 % after 24 months. In cases if target pressure could not be achieved the surgery was repeated. Conclusion. The absolute success originally achieved in all groups (96.3–98.4 %) was not persistent and after a 2-year observation, tended to disappear. The effect lasted longer in eyes after trabeculectomy with Glautex and Ex-PRESS. The hypotensive effect of primary antiglaucoma surgery was higher in penetrating operations.

Publisher

Real Time, Ltd.

Subject

Ophthalmology

Reference10 articles.

1. Egorov E.A., ed. Glaucoma. National guidelines. Moscow: GEOTAR-Media. 2013: 684–5 (in Russian)

2. EGS-European Glaucoma Society. Terminology and guidelines for glaucoma (4th edition). Publicomm srl; 2014: 170–2.

3. Anisimova S.Yu., Anisimov S.I., Rogacheva I.V. Long-term results of surgical treatment of refractory glaucoma using collagen drainage resistant to biodegradation. Glaucoma. 2011; 2: 28–33 (in Russian)

4. Slonimskij А., Alekseev I., Dolgij S., Korigodskij А. New biodegraded drainage Glautex in the surgical treatment of glaucoma. Natsional’nyi zhurnal glaukoma. 2012; 12 (4): 55–9 (in Russian)

5. Slonimskiy A.Y., Alekseev I.B., Dolgiy S.S. New possibilities of excessive postoperative scarring prophylaxis by glaucoma surgery. Oftal'mologiya. 2012; 9 (3): 36–40 (in Russian). https://doi.org/10.18008/1816-50952012-3-36-40

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