Factors of reduced bone mineral density in children with Turner syndrome

Abstract

Decreased bone mineral mass is one of the significant somatic problems for adolescents with Turner syndrome. The results of our own study, which estimates the state of bone mineral density in children with Turner syndrome depending on age, karyotype variant, spontaneous or stimulated onset of sexual development are present in the publication. A high frequency of bone mineral density deficiency in patients with Turner syndrome was established, regardless of the presence of puberty. Changes in bone density in girls with spontaneous puberty are less common. The difference in bone mineral density between patients with Turner syndrome and the control group from the age of 11 years was shown. Positive effect of replacement estrogen therapy on bone tissue condition in Turner syndrome is shown.