γA Gene Repeats Polymorphism for the Analysis of Haplotypes of Abnormal Hemoglobins-Reference-Cited by-同舟云学术

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γA Gene Repeats Polymorphism for the Analysis of Haplotypes of Abnormal Hemoglobins

Published:2014-09-29 Issue:2 Volume:4 Page:1935
ISSN:2039-4365
Container-title:Thalassemia Reports
language:en
Short-container-title:Thalassemia Reports

Author:

Akar Nejat,Sipahi Kadir,Akar Ece,Yilmaz Erkan

Abstract

Aim of this study was to analyze γ A gene repeat polymorphism for the analysis of haplotypes of hemoglobin (Hb) variants such as Hb S, Hb D-Punjab, Hb O-Arab. Sickle cell cases had mainly Benin and Arab/Indian haplotype. We found three different haplotypes among Hb S, Hb O Arab and Hb D-Punjab cases. We named these three variants as Anatolian-1 and Anatolian-2 and Asian. Our data revealed that Hb O Arab may arise twice one from Asia and the other from Europe.

Publisher

MDPI AG

Link

https://www.mdpi.com/2039-4365/4/2/1935/pdf

Reference10 articles.

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4. A novel approach to rapid determination of bS-globin haplotypes: sequencing of the A g-IVSII region;Vinson;Hemoglobin,2004

5. Sequence variations in the 5’ flanking and IVS-II regions of the G γ- and A γ-globin genes of β S chromosomes with five different haplotypes;Lanclos;Blood,1991

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