Abstract
The most prevalent infection that causes chronic gastritis, gastric ulcers, and gastric cancer is Helicobacter pylori infection. Recent research has implicated H. pylori in the pathogenesis of non-gastrointestinal diseases such as cardiovascular, autoimmune, and metabolic disorders. In addition, since H. pylori is believed to be implicated in insulin resistance, numerous studies have been conducted to determine the relationship between H. pylori infection and nonalcoholic fatty liver diseases (NAFLD), but the results have been contested. The purpose of this study is to determine the relationship between H. Pylori infection and nonalcoholic fatty liver diseases. One hundred patients were examined via urea breath test for the presence of H. pylori infection and vibration-controlled transient elastography for the diagnosis of non-alcoholic fatty liver disease. After adjusting for other variables, age, body mass index (BMI), and H. pylori infection were associated with elastography 248dB/m. Infection with H. pylori contributes to the development of NAFLD, and its eradication may influence prognosis.
Subject
Industrial and Manufacturing Engineering,Environmental Engineering
Reference34 articles.
1. Narayanan M, Reddy K, Marsicano E. Peptic ulcer disease and Helicobacter pylori infection. Mo Med 2018;115:219-24.
2. Waluga M, Kukla M, Zorniak M. From the stomach to other organs: Helicobacter pylori and the liver. World J Hepatol 2015;18:2136-46.
3. Kim D, Kim WR. Non-obese. Clin Gastroenterol Hepatol 2017;15:474-85.
4. Younossi Z, Anstee M, Marietti M. Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention. Nat Rev Gastroenterol Hepatol 2018;15:11-20.
5. Anstee M, Targher G, Day P. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat Rev Gastroenterol Hepatol 2013;10:330-44.