Acquired hemophilia A in a case of purple urine bag syndrome

Author:

Gammaldi Vittoria,Guida Anna,Bologna Carolina,De Sena Antonietta,Lugarà Marina,De Luca Claudio,Granato Corigliano Fabio,Guerra Mariavittoria,Oliva Gabriella,Mocerino Luca,Zarrella Aquilino Flavio,Coppola Maria Gabriella,Nuzzo Vincenzo,Tirelli Paolo,Madonna Pasquale

Abstract

The rare hemorrhagic disorder known as acquired hemophilia A (AHA) is brought on by the spontaneous development of autoantibodies against coagulation factor VIII (FVIII). It may be secondary to autoimmune diseases or cancers, or it may be idiopathic. Less than 10% of cases may have an infection as a secondary cause. We present the case of a 90-year-old anemic woman who was admitted to the hospital. She contracted a urinary tract infection (UTI) while in the hospital, and her urine took on a distinct purple hue. She had poor hemorrhagic manifestations and a prolonged partial thromboplastin time. After ruling out autoimmune and neoplastic causes, we diagnosed AHA as a result of a UTI caused by Enterococcus faecalis.

Publisher

PAGEPress Publications

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