Author:
Fugazzola Paola,Coccolini Federico,Nita Gabriela E.,Montori Giulia,Corbella Davide,Adesunkanmi Abdulrasheed R.K.,Aluffi Alessandro,Baiocchi Gianluca,Biffl Walter,Catena Fausto,Celotti Andrea,Cheynel Nicolas,Colledan Michele,Cui Yunfeng,Di Saverio Salomone,Faro Mario Paulo Jr.,Faruk Karateke,Fraga Gustavo Pereira,Gerych Igor,Gomes Carlos Augusto,Guercioni Gianluca,Isik Arda,Khokha Vladimir,Kluger Yoram,Kong Victor,Leppaniemi Ari,Manfredi Roberto,Massalou Damien,Moore Eugeene,Naidoo Noel,Pereira Bruno Monteiro Tavares,Piazzalunga Dario,Pisano Michele,Poiasina Elia,Poletti de Chaurand Eugenio,Rat Patrick,Sakakushev Boris,Sartelli Massimo,Siribumrungwong Boonying,Solaini Leonardo,Tomasoni Matteo,Vettoretto Nereo,Yuan Kuo-Ching,Ansaloni Luca
Abstract
Peritoneal adhesion index (PAI) is a score based on appearance and distribution of peritoneal adhesions. The study aims to assess the validity of PAI in order to standardize the definition of peritoneal adhesions. The study includes an expert survey to assess the feasibility of the score and a prospective observational and multicenter trial to assess its validity. 96% of surgeons of the survey consider PAI a useful tool. From January 2013 to March 2015, 205 patients were enrolled to undergo a surgical intervention for bowel obstruction caused by peritoneal adhesions in 21 centers. PAI was significantly higher in the population with previous surgery (P=0.043) and in patients who underwent two previous surgical interventions, if compared to those with only one previous intervention (P=0.012). Length of surgery was significantly longer in patients with higher PAI (P<0.001). Patients with a higher PAI showed a clinically higher risk for early bowel re-obstruction and for early re-intervention. The AUC of the ROC curve for early re-occlusion is 0.8. PAI can be considered a feasible and useful score.