Chronic mucocutaneous candidiasis due to signal transducer and activator of transcription 1 mutation in a Saudi patient: a case report-Reference-Cited by-同舟云学术

Chronic mucocutaneous candidiasis due to signal transducer and activator of transcription 1 mutation in a Saudi patient: a case report

Published:2024-07-03 Issue: Volume: Page:
ISSN:2036-7406
Container-title:Dermatology Reports
language:
Short-container-title:Dermatol Reports

Author:

Alakeel Abdullah,Nabil Nagshabandi Khalid^ORCID,Alsalhi Abdulaziz^ORCID

Abstract

Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency condition caused by a genetic abnormality that increases the risk of recurrent and persistent skin, nail and mucous membrane infections with Candida species, typically Candida albicans. Signal transducer and activator of transcription 1 (STAT 1) gene mutation is a genetic trigger that causes CMC, which increases the risk of infections, multisystem disorders and cancer susceptibility. We describe the first case of a Saudi female patient with clinical features of CMC with an underlying (STAT 1) gene mutation.

Publisher

PAGEPress Publications

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