A Rare Occurrence of Neonatal Nephroblastoma in Sub-Saharan Africa: A Case Report and Management in a Resource-Constrained Region

Author:

Matondo Féfé Khuabi1,Budiongo Aléine Nzazi1,Tady Bruno Muyala2,Lebwaze Bienvenu Massamba3,Lelo Michel Tshikwela4,Gini-Ehungu Jean Lambert1,Mwepu Idesbald5,Nkidiaka Emmanuel Dimbu2,Aloni Michel Ntetani1

Affiliation:

1. Division of Hematology/Oncology and Nephrology, Department of Pediatrics, University Hospital of Kinshasa School of Medicine, University of Kinshasa, Democratic Republic of Congo

2. Division of Neonatology, Department of Pediatrics, University Hospital of Kinshasa School of Medicine, University of Kinshasa, Democratic Republic of Congo

3. Division of Pathology, University Hospital of Kinshasa School of Medicine, University of Kinshasa, Democratic Republic of Congo

4. Division of Radiology, University Hospital of Kinshasa School of Medicine, University of Kinshasa, Democratic Republic of Congo

5. Division of Pediatric Surgery, Department of Surgery, University Hospital of Kinshasa School of Medicine, University of Kinshasa, Democratic Republic of Congo

Abstract

Neonatal nephroblastoma has been rarely reported in African neonate. A premature newborn (a 5-day-old male) was transferred with a history of neonatal abdominal mass. Ultrasonography revealed 75×46 mm, well-defined mass with mixed echogenicity replacing the right kidney. The patient underwent right radical nephrectomy and the tumor was confirmed to be a blastemal predominant Wilms’ tumor by the histopathological examination and has an unfavorable prognosis. The child died secondary to multiple organ failure, three days after surgery. Our case report serves to remind us the need to bear in mind the possibility of the diagnosis of neonatal nephroblastoma in neonate with renal mass.

Publisher

SAGE Publications

Subject

Oncology,Histology

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