Myxofibrosarcoma: A Diagnostic Pitfall

Author:

Castronovo Charlotte1,Arrese Jorge E.2,Quatresooz Pascale2,Nikkels Arjen F.1

Affiliation:

1. Departments of Dermatology, University Hospital of Liège, Liège, Belgium

2. Departments of Dermatopathology, University Hospital of Liège, Liège, Belgium

Abstract

Myxofibrosarcoma (MFS) is a variant of the group of malignant fibrous histiocytomas. It is one of the most aggressive types of soft tissue neoplasms. The clinical presentation is not pathognomonic and the histological aspects are highly heterogenous, frequently delaying the diagnosis or leading to misdiagnosis. Complementary histochemical and immunohistochemical stainings are mandatory to achieve the diagnosis of MFS. A 78-year-old male patient is presented illustrating this diagnostic pitfall. Extensive surgery followed by radiotherapy is the first choice treatment.

Publisher

SAGE Publications

Subject

Oncology,Histology

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