Author:
Meena Durga Shankar,Bohra Gopal Krishana
Abstract
Sjogren’s syndrome (SS) is a chronic systemic autoimmune disease, characterized by lymphocytic infiltration of lacrimal and salivary glands. Although extra glandular manifestations are uncommon, they can occur with the musculoskeletal, renal, pulmonary and hematological disease. We report the case of a 35-year-old woman presented to us with persistent unexplained bicytopenia (anemia and thrombocytopenia). Antinuclear antibody and direct Coombs test were positive. Anti-Ro/SSA and anti-La/SSB antibodies were also positive in high titer. The final diagnosis of primary SS with autoimmune cytopenia was made. Cytopenias in SS are rarely reported. Our case illustrates that clinically significant cytopenias may present as an extraglandular manifestation of SS.
Reference16 articles.
1. Clinical analysis of primary Sjogren’s syndrome complicating anemia;Zhou;Clin Rheumatol,2010
2. Renal involvement in primary Sjogren’s syndrome: a clinicopathologic study;Maripuri;Clin J Am Soc Nephrol,2009
3. Kidney biopsy findings in primary Sjogren’s syndrome;Kidder;Nephrol Dial Transplant,2015
4. Haematological manifestations of primary Sjogren’s syndrome: a clinicopathological study;Ramakrishna;Q J Med,1992
5. Sjogren’s syndrome and pure red cell aplasia. Letter;Giordano;Clin Exp Rheumatol,1996
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