Author:
Kimata Takahisa,Kaneko Kauznari,Takahashi Masaya,Yamanouchi Sohsaku,Tsuji Shoji,Kino Minoru
Abstract
It is known that ceftriaxone administration is associated with biliary pseudolithiasis, although the development of urolithiasis has been rarely reported. We encountered a young male with bacterial meningitis complicated by urinary precipitates composed of ceftriaxonecalcium salt which is confirmed by high-performance liquid chromatography. This patient suggested that ceftriaxone significantly increased urinary excretion of calcium, which may be linked to ceftriaxone-related urolithiasis or sludge. It is therefore worthwhile to monitor the levels of urinary calcium to creatinine ratio in patients on ceftriaxone, as they may be at greater risk for developing large stones and renal damage.
Cited by
3 articles.
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1. Safety of ceftriaxone in paediatrics: a systematic review;Archives of Disease in Childhood;2020-03-06
2. Kidney Stones and Ceftriaxone;EMJ Urology;2015-01-20
3. Ceftriaxone;Reactions Weekly;2013-04