Lemierre syndrome presenting as acute mastoiditis in a 2-year-old girl with congenital dwarfism

Author:

Fischer Jason B.ORCID,Prout Andrew,Blackwood R. Alexander,Warrier Kavita

Abstract

Lemierre syndrome is defined by septic thrombophlebitis of the internal jugular vein caused by <em>Fusobacterium</em>. Historically, these infections originate from the oropharynx and typically are seen in older children, adolescents and young adults. More recently, otogenic sources in younger children have been described with increasing frequency. We present a case of a two-year old, who initially developed an otitis media with perforation of the tympanic membrane and went on to develop mastoiditis and non-occlusive thrombosis of the venous sinus and right internal jugular vein. <em>Fusobacterium necrophorum</em> was grown from operative cultures of the mastoid, ensuing computed tomography scan revealed occlusion of the internal jugular vein and the patient was successfully treated with clindamycin, ciprofloxacin and enoxaparin. This case demonstrates the importance of considering <em>Fusobacterium</em> in otogenic infections and the consideration of Lemierre syndrome when <em>F. necrophorum</em> is identified.

Publisher

MDPI AG

Subject

Infectious Diseases

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Lemierre’s syndrome in pediatric population;Polski Przegląd Otorynolaryngologiczny;2024-02-27

2. Mastoiditis and Hearing Loss in Children;Hearing Loss in Congenital, Neonatal and Childhood Infections;2023

3. The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways;Frontiers in Aging Neuroscience;2022-06-23

4. Determination of the Role of Fusobacterium Nucleatum in the Pathogenesis in and Out the Mouth;PRILOZI;2020-06-01

5. Mastoiditis with concomitant Lemierre's syndrome;The American Journal of Emergency Medicine;2019-06

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