Attention/Deficit Hyperactivity Disorder in Adolescent and Young Adult Males With Fragile X Syndrome-Reference-Cited by-同舟云学术

Attention/Deficit Hyperactivity Disorder in Adolescent and Young Adult Males With Fragile X Syndrome

Published:2022-04-20 Issue:3 Volume:127 Page:213-230
ISSN:1944-7558
Container-title:American Journal on Intellectual and Developmental Disabilities
language:en
Short-container-title:

Author:

Klusek Jessica¹,O'Connor Shannon L.¹,Hickey Alexandra¹,Hills Kimberly J.¹,Abbeduto Leonard²,Roberts Jane E.³

Affiliation:

1. Jessica Klusek, Shannon L. O'Connor, Alexandra Hickey and Kimberly J. Hills, University of South Carolina

2. Leonard Abbeduto, University of California Davis Health

3. Jane E. Roberts, University of South Carolina

Abstract

Abstract This study characterized the rates of attention-deficit/hyperactivity disorder (ADHD) in adolescent and young adult males with fragile X syndrome (FXS) using a multi-method approach integrating a DSM-based parent interview (Children's Interview for Psychiatric Syndromes; P-ChIPS, Fristad et al., 1998) and a parent rating scale (Child Behavior Checklist; CBCL, Achenbach, 2001). Thirty-one males with FXS, aged 16–24 years, participated. Forty-two percent met DSM-5 criteria for ADHD and 35% exceeded the CBCL cut-offs. Agreement between the two classification methods was fair (κ = 0.38). Autism symptom severity and nonverbal cognitive ability did not predict ADHD diagnoses/symptoms. Results show high rates of ADHD in males with FXS during late adolescence and young adulthood, which are not accounted for by impaired nonverbal cognitive skills or autism symptom severity. DSM-based ADHD-specific scales are recommended over broadband symptom scales to improve accurate identification.

Publisher

American Association on Intellectual and Developmental Disabilities (AAIDD)

Subject

Psychiatry and Mental health,Neurology (clinical),Arts and Humanities (miscellaneous),Developmental and Educational Psychology,Neuropsychology and Physiological Psychology,General Medicine,Pediatrics, Perinatology and Child Health

Link

https://meridian.allenpress.com/ajidd/article-pdf/127/3/213/3047057/i1944-7558-127-3-213.pdf

Reference97 articles.

1. Abbeduto, L., Thurman, A. J., McDuffie, A., Klusek, J., Feigles, R. T., Brown, W. T., Harvey, D. J., Adayev, T., LaFauci, G., & Dobkins,C. (2019). ASD comorbidity in fragile X syndrome: Symptom profile and predictors of symptom severity in adolescent and young adult males. Journal of Autism and Developmental Disorders, 49(3), 960– 977. https://doi.org/10.1007/s10803-018-3796-2

2. Achenbach, T. M. (2001). Child behavior checklist for ages 6 to 18. University of Vermont, Research Center for Children,Youth, and Families.

3. Aman, M. G., Singh, N. N., Stewart, A. W., & Field,C. J. (1985). The aberrant behavior checklist: A behavior rating scale for the assessment of treatment effects. American Journal of Mental Deficiency, 89, 485– 491. https://doi.org/10.1037/t10453-000

4. American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). American Psychiatric Association.

5. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text revision). American Psychiatric Association. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). American Psychiatric Association.

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