Which one is more dangerous in childhood Rotavirus or Adenovirus?

Abstract

Objective: Determination of the frequency of Rotavirus and Adenovirus in patients diagnosed with gastroenteritis in the Pediatric Polyclinic of our hospital by immunochromatographic method and retrospective evaluation of the change in the distribution of the agent according to age, gender and vaccination status. Method: Those patients with complaints of diarrhea, vomiting, dehydration, and fever as well as those diagnosed with acute gastroenteritis were evaluated by taking fresh stool samples between January 2015 and November 2020. The data were presented using descriptive statistics. Results: The number of acute gastroenteritis patients included in the study was 1,192. The mean age of the patients was 18±SD months (min: 1 month, max: 180 months). Adenovirus and Rotavirus antigens were detected in 10% of all cases (n=119). Rotavirus antigen was positive in 6.6% (n=78) and Adenovirus antigen was positive in 3.1% (n=38) of all cases. The hospitalization rate was 5.1 times higher in Rotavirus positive cases (p<0.001). It was observed that fever and vomiting were statistically higher in patients with Adenovirus or Rotavirus positive. (p=0.001). Conclusion: It has been shown that Rotavirus should be kept in mind, especially in children with severe vomiting/diarrhea leading to dehydration. Therefore, Rotavirus vaccination is very important in early childhood.