Methodologies to Increase the Level of Evidence of Real-life Proton Therapy in Head and Neck Tumors-Reference-Cited by-同舟云学术

Methodologies to Increase the Level of Evidence of Real-life Proton Therapy in Head and Neck Tumors

Published:2021-06-01 Issue:1 Volume:8 Page:328-338
ISSN:2331-5180
Container-title:International Journal of Particle Therapy
language:en
Short-container-title:

Author:

Dionisi Francesco¹²,Widesott Lamberto¹,Van Vulpen Marco³,Fuller Clifton David⁴,Frondizi Rocco⁵,Meneguzzo Marco⁵⁶,Blanchard Pierre⁷,Amichetti Maurizio¹,Sanguineti Giuseppe²

Affiliation:

1. Proton Therapy Unit, Department of Oncology, Azienda Provinciale per I Servizi Sanitari (APSS), Trento, Italy

2. Department of Radiation Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Regina Elena National Cancer Institute, Rome, Italy

3. Proton Therapy Center, Delft, the Netherlands

4. Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA

5. Department of Management and Law, Tor Vergata University of Rome, Rome, Italy

6. Centre for Organisational Research, Health and Public Management, Università della Svizzera Italiana (USI), Lugano, Switzerland

7. Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France

Abstract

Abstract This review aims to present and assess available and new methodologies to increase the clinical evidence of proton therapy data for patients with head and neck cancer. Despite the increasing number of scientific reports showing the feasibility and effectiveness of proton therapy in head and neck cancer, clinical evidence on the potential benefits of its use remains low for several reasons. In this article, the pros and cons of consolidated and new methodologies in this setting such as randomized clinical trials, the model-based approach, and the use of prospective multicentric registries will be detailed.

Publisher

International Journal of Particle Therapy

Subject

Radiology, Nuclear Medicine and imaging,Atomic and Molecular Physics, and Optics

Link

http://meridian.allenpress.com/theijpt/article-pdf/8/1/328/2880289/i2331-5180-8-1-328.pdf

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