Isolation of the Uterotonic Principle from Leonurus Artemisia, the Chinese Motherwort-Reference-Cited by-同舟云学术

Isolation of the Uterotonic Principle from Leonurus Artemisia, the Chinese Motherwort

Published:1976-01 Issue:04 Volume:04 Page:373-382
ISSN:0192-415X
Container-title:The American Journal of Chinese Medicine
language:en
Short-container-title:Am. J. Chin. Med.

Author:

Kong Y. C.¹,Yeung H. W.¹,Cheung Y. M.²,Phil M.²,Hwang J. C.²,Chan Y. W.¹,Law Y. P.¹,Ng K. H.¹,Yeung C. H.²

Affiliation:

1. Biochemistry Department and Interdisciplinary Research Unit in Chinese Medicinal Material, The Chinese University of Hong Kong, Hong Kong

2. Physiology Department, Faculty of Medicine, The University of Hong Kong, Hong Kong

Abstract

A search in ancient Chinese medicinal literature and modern phytochemical reference indicates that the therapeutic value of Leonurus artemisia (I-mu ts'ao, the Chinese motherwort) might reside in a uterotonic principle present in leaves. Leonurine (4-guanidino-n-butyl syringate) was isolated from fresh and dry leaves of Leonurus artemisia. The uterotonic effect of leonurine was demonstrated in rat uterus in vitro. Results from this study suggest that functional phytochemistry based on ethnobotanical experience could lead to development of new and effective drugs from Chinese medicine.

Publisher

World Scientific Pub Co Pte Lt

Subject

Complementary and alternative medicine,General Medicine

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0192415X76000470

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