Control of COVID-19 outbreak using an extended SEIR model

Author:

McQuade Sean T.12,Weightman Ryan12,Merrill Nathaniel J.3,Yadav Aayush45,Trélat Emmanuel6,Allred Sarah R.45,Piccoli Benedetto12

Affiliation:

1. Department of Mathematical Sciences, Rutgers University–Camden, Camden, NJ 08102, USA

2. Center for Computational and Integrative Biology, Rutgers University–Camden, Camden, NJ 08102, USA

3. Pacific Northwest National Laboratory (PNNL), Richland, WA 99354, USA

4. Department of Psychology, Rutgers University–Camden, Camden, NJ 08102, USA

5. Senator Walter Rand Institute for Public Affairs, Rutgers University–Camden, Camden, NJ 08102, USA

6. Laboratoire Jacques-Louis Lions, Sorbonne Université, 75005 Paris, France

Abstract

The outbreak of COVID-19 resulted in high death tolls all over the world. The aim of this paper is to show how a simple SEIR model was used to make quick predictions for New Jersey in early March 2020 and call for action based on data from China and Italy. A more refined model, which accounts for social distancing, testing, contact tracing and quarantining, is then proposed to identify containment measures to minimize the economic cost of the pandemic. The latter is obtained taking into account all the involved costs including reduced economic activities due to lockdown and quarantining as well as the cost for hospitalization and deaths. The proposed model allows one to find optimal strategies as combinations of implementing various non-pharmaceutical interventions and study different scenarios and likely initial conditions.

Funder

NSF CMMI

Publisher

World Scientific Pub Co Pte Ltd

Subject

Applied Mathematics,Modeling and Simulation

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