LOOKING FOR NEW PARADIGMS TOWARDS A BIOLOGICAL-MATHEMATICAL THEORY OF COMPLEX MULTICELLULAR SYSTEMS

Author:

BELLOMO NICOLA1,FORNI GUIDO2

Affiliation:

1. Department of Mathematics, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy

2. Department of Clinical and Biological Sciences, Ospedale San Luigi Gonzaga, Università degli Studi di Torino, 10043 Orbassano, Italy

Abstract

This paper deals with the development of new paradigms based on the methods of the mathematical kinetic theory for active particles to model the dynamics of large systems of interacting cells. Interactions are ruled, not only by laws of classical mechanics, but also by a few biological functions which are able to modify the above laws. The paper technically shows, also by reasoning on specific examples, how the theory can be applied to model large complex systems in biology. The last part of the paper deals with a critical analysis and with the indication of research perspectives concerning the challenging target of developing a biological-mathematical theory for the living matter.

Publisher

World Scientific Pub Co Pte Lt

Subject

Applied Mathematics,Modelling and Simulation

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