THE DYNAMICS OF HIV/AIDS MODEL WITH FRACTAL-FRACTIONAL CAPUTO DERIVATIVE

Author:

ULLAH SAIF1,ALTANJI MOHAMED2,KHAN MUHAMMAD ALTAF34,ALSHAHERI AHMED5,SUMELKA WOJCIECH6

Affiliation:

1. Department of Mathematics, University of Peshawar, Khyber Pakhtunkhwa 25120, Pakistan

2. Department of Mathematics, College of Science, King Khalid University, Abha 61413, Saudi Arabia

3. Faculty of Natural and Agricultural Sciences, University of the Free State, South Africa

4. Department of Mathematics, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia

5. Department of Mathematics, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia

6. Institute of Structural Analysis, Poznan University of Technology, Piotrowo 5 Street, 60-965 Poznan, Poland

Abstract

The human immunodeficiency virus (HIV) is a major global public health issue and causes millions of deaths around the globe. The most severe phase of HIV infection is known as AIDS. In recent years, a number of mathematical models based on classical integer-order derivative have been developed to analyze the insight dynamics of HIV/AIDS. This paper presents the transmission dynamics of HIV/AIDS using fractional order (FO) and a fractal-fractional order compartmental model with the power-law kernel. In the first phase, the proposed model is formulated using the Caputo-type fractional derivative. The basic properties such as the solution positivity and existence as well as uniqueness of the fractional model are presented. The equilibria and the basic reproductive number [Formula: see text] are evaluated. Further, using fractional stability concepts the stability of the model (both local and global) around the equilibrium is presented in the disease-free case. In addition, the fractional model is solved numerically, and the graphical results with many values of [Formula: see text] are shown. In the second phase, the concept of a fractal-fractional (FF) operator is applied to obtain a more generalized model that addresses the dynamics of HIV/AIDS. The uniqueness and existence of the solutions of the FF-based model are shown via the Picard–Lindelof approach while the modified Adams–Bashforth method is utilized to present the numerical solution. Detailed numerical simulations are presented for various values fractional as well as the fractal orders, [Formula: see text] and [Formula: see text] respectively. The graphical results reveal that the FF-based model provides biologically more feasible results than the models in fractional and classical integer-order cases.

Funder

Deanship of Scientific Research at King Khalid University

National Science Centre, Poland

Publisher

World Scientific Pub Co Pte Ltd

Subject

Applied Mathematics,Geometry and Topology,Modeling and Simulation

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