ANALYSIS OF A NONLINEAR DYNAMICAL MODEL OF HEPATITIS B DISEASE

Author:

LIU PEIJIANG12,SHEN WEI-YUN34,DIN ANWARUD5

Affiliation:

1. School of Statistics and Mathematics, Guangdong University of Finance and Economics, Big Data and Educational Statistics Application Laboratory, Guangzhou 510320, P. R. China

2. School of Statistics and Mathematics, Guangdong University of Finance and Economics, Guangzhou 510320, P. R. China

3. Zhejiang Provincial Key Laboratory of Media Biology and Pathogenic Control, Central Laboratory, Huzhou University, Huzhou 313000, P. R. China

4. The First People’s Hospital of Huzhou, 158 Guangchanghou Road, Huzhou 313000, P. R. China

5. Department of Mathematics, Sun Yat-sen University, Guangzhou 510275, P. R. China

Abstract

Mathematical epidemiology holds prime importance for comprehending the dynamics of infectious diseases. Consequently, mathematical model of hepatitis B with fractional-order derivative under Caputo sense is primarily focused in this research. The analysis of the required solution is qualitatively derived by applying the fixed-point theory approach. By perturbing the proposed model, the Ulam–Hyer’s stability techniques are further derived. To achieve the iterative series solution of the proposed system of hepatitis, the modified Euler method like Taylor’s series method is utilized. For validation and importance of the fractional operators, sufficient significant numerical results at various fractional orders are presented and compared them with the integer order. It is inferred from this research that, by using the fractional-order method, the transmission mechanism of hepatitis B disease can be acutely revealed. This study may provide positive theoretical support for the prevention and treatment of hepatitis B disease.

Funder

the National Natural Science Foundation of P. R. China

Guangzhou Science and Technology Innovation General Project

Young Innovative Talents Project of Guangdong Provincial Department of Education

Guangdong Basic and Applied Basic Research Foundation

the Fundamental Research Funds for the central Universities, Sun Yat-sen University

Publisher

World Scientific Pub Co Pte Ltd

Subject

Applied Mathematics,Geometry and Topology,Modeling and Simulation

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