Current Understanding and Prospects of Silver Nanoparticles-Based Biosensor

Abstract

Due to their distinctive optical potential, controlled plasmonic features, control over size and shape, and ability to manipulate their localized surface plasmon resonance (LSPR) and their response to their surroundings, silver nanoparticle attracts special attention in the fields of the biosensor. Silver (Ag) is an appealing tool in many domains, including diagnosis, medicine delivery, environment, electronics, and as an antibacterial agent. Ag nanoparticle applications are ubiquitous today in the fields of biosensors. Numerous studies have demonstrated the effectiveness of using Ag nanoparticles to improve the specific detection of clinical indicators. The development of nanotechnology has greatly benefited the field of biosensors since nanomaterials have a high surface-to-volume ratio that enables them to operate with greater sensitivity and effectiveness. Utilizing interdisciplinary study in biology, chemistry, and material science, recent advancements in nanotechnology encouraged the manufacture of nanomaterials in a variety of shapes and sizes. In the context of disease diagnosis, this review highlighted the use of Ag nanoparticles in biosensors to detect small molecules to bigger entire cells. This paper also discusses how to make a glucose biosensor more sensitive. It describes how the detection performance of biomolecules including DNA, protein, tiny molecules, and complete cells can be improved. For future applications in the field of diagnosis, this review helps in developing an overall understanding of the clinical importance of Ag nanoparticles. These biosensors can be implemented in the field of diagnosis to speed up the response time.