Nanoparticles in Joint Arthroplasties

Abstract

Joint arthroplasty, specifically total knee arthroplasty (TKA) and total hip arthroplasty (THA), are two of the highest value surgical procedures. Over the last several decades, the materials utilized in these surgeries have improved and increased device longevity. However, with an increased incidence of TKA and THA surgeries in younger patients, it is crucial to make these materials more durable. The addition of nanoparticles is one technology that is being explored for this purpose. This review focuses on the addition of nanoparticles to the various parts of arthroplasty surgery comprising of the metallic, ceramic, or polyethylene components along with the bone cement used for fixation. Carbon additives proved to be the most widely studied, and could potentially reduce stress shielding, improve wear, and enhance the biocompatibility of arthroplasty implants.