Bactericidal efficiency of porphyrin systems

Author:

Habermeyer B.1,Chilingaryan T.1,Guilard R.12

Affiliation:

1. PorphyChem SAS, Dijon 21000, France

2. Institut de Chimie Moléculaire de l’Université de Bourgogne, ICMUB, UMR CNRS 6302, Université de Bourgogne Franche-Comté, F-21078, France

Abstract

Photodynamic Inactivation is an innovative technique used to combat bacterial and viral infections which involves the use of photosensitizing agents along with light to generate cytotoxic reactive oxygen species able to kill bacteria and viruses. In the first section of this minireview, porphyrin-based fluorophores are shown to be remarkable dye candidates for PDI (photodynamic inactivation) applications. The second section is dedicated to the description of porphyrin-based antimicrobial materials and their potentialities for industrial applications such as in food packaging or antimicrobial medical devices and hygiene. Finally, the failings and perspectives of PDI are analyzed to demonstrate how the PDI technique could be an efficient and ecologically friendly antimicrobial technique.

Publisher

World Scientific Pub Co Pte Lt

Subject

General Chemistry

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