Antimicrobial photodynamic therapy against Staphylococcus aureus using zinc phthalocyanine and zinc phthalocyanine-integrated TiO2 nanoparticles-Reference-Cited by-同舟云学术

Antimicrobial photodynamic therapy against Staphylococcus aureus using zinc phthalocyanine and zinc phthalocyanine-integrated TiO2 nanoparticles

Published:2019-01 Issue:01n02 Volume:23 Page:206-212
ISSN:1088-4246
Container-title:Journal of Porphyrins and Phthalocyanines
language:en
Short-container-title:J. Porphyrins Phthalocyanines

Author:

Tunçel Ayça¹,Öztürk İsmail²,Ince Mine³,Ocakoglu Kasim³,Hoşgör-Limoncu Mine⁴,Yurt Fatma¹

Affiliation:

1. Institute of Nuclear Science, Department of Nuclear Applications, Ege University, Bornova, 35100, Izmir, Turkey

2. Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Izmir Katip Celebi University, Bornova, 35620, Izmir, Turkey

3. Department of Energy Systems Engineering, Faculty of Technology, Tarsus University, TR33400, Tarsus, Turkey

4. Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Ege University, Bornova, 35100, Izmir, Turkey

Abstract

Antibiotic resistance is an increasing healthcare problem worldwide. In the present study, the effects of antimicrobial photodynamic therapy (APDT) of ZnPc and ZnPc-integrated TiO2 nanoparticles (ZnPc-TiO[Formula: see text] were investigated against Staphylococcus aureus. A light emitting diode (LED) (630–700 nm, 17.4 mW/cm[Formula: see text] was used on S. aureus at different light doses (8 J/cm2 for 11 min, 16 J/cm2 for 22 min, 24 J/cm2 for 33 min) in the presence of the compounds under the minimum inhibitory concentration values. Both compounds showed similar phototoxicity toward S. aureus when high light doses (16 and 24 J/cm[Formula: see text] were applied. In addition, the success of APDT increased with an increasing light dose.

Publisher

World Scientific Pub Co Pte Lt

Subject

General Chemistry

Link

https://www.worldscientific.com/doi/pdf/10.1142/S1088424619500238

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