Cationic tetrapyrrolic macromolecules as new acetylcholinesterase inhibitors-Reference-Cited by-同舟云学术

Cationic tetrapyrrolic macromolecules as new acetylcholinesterase inhibitors

Published:2009-08 Issue:08n09 Volume:13 Page:893-902
ISSN:1088-4246
Container-title:Journal of Porphyrins and Phthalocyanines
language:en
Short-container-title:J. Porphyrins Phthalocyanines

Author:

Tian Tian¹,Weng Liwei¹,Wang Shaoru¹,Weng Xiaocheng¹,Zhang Lixia²,Zhou Xiang¹

Affiliation:

1. College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, PR China

2. College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, PR China

Abstract

A series of tetrapyrrolic macrocycles such as porphyrins, phthalocyanines and corroles were found to have inhibitory abilities toward acetylcholinesterase (AChE). Their structure-activity relationship was studied. Several compounds were found to have good inhibitory abilities, which could be developed as potential candidates of acetylcholinesterase (AchE) inhibitors.

Publisher

World Scientific Pub Co Pte Lt

Subject

General Chemistry

Link

https://www.worldscientific.com/doi/pdf/10.1142/S1088424609001169

Reference6 articles.

1. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states

2. Synthesis and Structure-Activity Relationships of Acetylcholinesterase Inhibitors: 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine Hydrochloride and Related Compounds

3. Synthesis and evaluation of cationic phthalocyanine derivatives as potential inhibitors of telomerase

4. Cationic Metal-Corrole Complexes: Design, Synthesis, and Properties of Guanine-Quadruplex Stabilizers

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