Construction of polyelectrolyte multilayer with anti-oxidative activity via amplified growth

Author:

Wang Shuo1,Zhang Congcong1,Cao Weijuan1

Affiliation:

1. Faculty of Pharmacy, Zhejiang Pharmaceutical University, Ningbo 315100, P. R. China

Abstract

Herein, precursor assembly of polyanion with pH sensitive molecule, Bis[2-(4-HydroxyPhenyl)BenzImidazole] (BHPBI), was reported to amplify layer-by-layer (LBL) exponential growth. The promoted polyelectrolyte diffusivity was responsible for the amplified LBL deposition efficiency. The release behavior of BHPBI and the anti-oxidant stress function of the film were both evaluated. The constructed multilayer film was tested to be potential drug loading and delivery system for BHPBI.

Funder

Science and Technology Plan Project of Zhejiang Provincial Drug Administration

Publisher

World Scientific Pub Co Pte Ltd

Subject

General Materials Science

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