AMPAR Encephalitis and Myasthenia Gravis in Systemic Lupus Erythematosus

Abstract

A 38-year-old lady was diagnosed with systemic lupus erythematosus (SLE) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) autoimmune encephalitis, fulfilling both classification criteria during her index admission. She was subsequently diagnosed with seropositive myasthenia gravis (MG) with a typical clinical presentation. Her SLE and AMPAR encephalitis were successfully treated with immunosuppressive therapy. Her MG responded well to anti-cholinesterase inhibitors. We report a distinctive case with the association of three rare autoimmune diseases in an individual.