PREPARATION AND PROPERTY STUDIES OF Zn3P2/CALCIUM ALGINATE

Abstract

Zn 3 P 2 is an acute and effective rodenticide used widely to protect grains in stores and domestically to kill rodents. This study aims to postpone the time of poisoning symptoms after eating Zn 3 P 2 and improve the effect of killing rodents. Zn 3 P 2/calcium alginate ( Zn 3 P 2/ CA ) was synthesized through the reaction of sodium alginate and calcium chloride by the reversed-phase microemulsion method and then loaded with Zn 3 P 2 technical. It was characterized by X-ray diffractometer, laser particle size analyzer, scanning electron microscope (SEM) and transmission electron microscopy (TEM). The drug loading capacity, slow-controlled release performances and toxic effects were also investigated. The results showed that Zn 3 P 2/ CA was spherical, average particle size was 353.9 nm, and particle dispersion index (PDI) was 0.195. The mass ratios of calcium alginate and Zn 3 P 2 technical ( CA / Zn 3 P 2) had significant impacts to drug loading capacity and slow-controlled release performances of Zn 3 P 2/ CA . The palatability and efficacy of Zn 3 P 2/ CA were significantly improved and enhanced compared with Zn 3 P 2 technical. The results showed that Zn 3 P 2/ CA presented high loading efficiency, commendable sustained-release performance and good environmental compatibility, and this delivery carrier may be extended to other slow-controlled release and high-efficient pesticide formulation in future.