POLARIZATION IMAGING AND SCATTERING MODEL OF CANCEROUS LIVER TISSUES

Author:

LI DONGZHI12,HE HONGHUI1,ZENG NAN1,DU E12,LIAO RAN1,HE YONGHONG1,MA HUI12,LIU SHAOXIONG3,LI MINGHUA3

Affiliation:

1. Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China

2. Department of Physics, Tsinghua University, Beijing 100084, P. R. China

3. Shenzhen Sixth People's Hospital (Nanshan Hospital), Huazhong University of Science and Technology, Union Shenzhen Hospital, Shenzhen 518052, P. R. China

Abstract

We apply different polarization imaging techniques for cancerous liver tissues, and compare the relative contrasts for difference polarization imaging (DPI), degree of polarization imaging (DOPI) and rotating linear polarization imaging (RLPI). Experimental results show that a number of polarization imaging parameters are capable of differentiating cancerous cells in isotropic liver tissues. To analyze the contrast mechanism of the cancer-sensitive polarization imaging parameters, we propose a scattering model containing two types of spherical scatterers and carry on Monte Carlo simulations based on this bi-component model. Both the experimental and Monte Carlo simulated results show that the RLPI technique can provide a good imaging contrast of cancerous tissues. The bi-component scattering model provides a useful tool to analyze the contrast mechanism of polarization imaging of cancerous tissues.

Publisher

World Scientific Pub Co Pte Lt

Subject

Biomedical Engineering,Atomic and Molecular Physics, and Optics,Medicine (miscellaneous),Electronic, Optical and Magnetic Materials

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