Biomedical microwave-induced thermoacoustic imaging

Author:

Liu Qiang1ORCID,Liang Xiao1ORCID,Qi Weizhi1,Gong Yubin2,Jiang Huabei3,Xi Lei14

Affiliation:

1. Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, P. R. China

2. School of Electrical Science and Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan, 610054, P. R. China

3. Department of Medical Engineering, University of South Florida, Tampa, FL 33620, USA

4. Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, Guangdong, 518055, P. R. China

Abstract

Microwave-induced thermoacoustic imaging (MTAI) has emerged as a potential biomedical imaging modality with over 20-year growth. MTAI typically employs pulsed microwave as the pumping source, and detects the microwave-induced ultrasound wave via acoustic transducers. Therefore, it features high acoustic resolution, rich electromagnetic contrast, and large imaging depth. Benefiting from these unique advantages, MTAI has been extensively applied to various fields including pathology, biology, material and medicine. Till now, MTAI has been deployed for a wide range of biomedical applications, including cancer diagnosis, joint evaluation, brain investigation and endoscopy. This paper provides a comprehensive review on (1) essential physics (endogenous/exogenous contrast mechanisms, penetration depth and resolution), (2) hardware configurations and software implementations (excitation source, antenna, ultrasound detector and image recovery algorithm), (3) animal studies and clinical applications, and (4) future directions.

Funder

National Natural Science Foundation of China

Guangdong Science and Technology Department

Publisher

World Scientific Pub Co Pte Ltd

Subject

Biomedical Engineering,Atomic and Molecular Physics, and Optics,Medicine (miscellaneous),Electronic, Optical and Magnetic Materials

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