A High-Sensitivity and Low-Power Circuit for the Measurement of Abnormal Blood Cell Levels

Author:

Nagulapalli R.1,Hayatleh K.1,Barker S.1,Tammam A. A.1,Lidgey F. J.1,Yassine N.1

Affiliation:

1. School of Engineering, Computing and Mathematics, Oxford Brookes University, Wheatley Campus, Wheatley, Oxford OX33 1HX, UK

Abstract

This paper describes a technique to detect blood cell levels based on the time-period modulation of a relaxation oscillator loaded with an Inter-Digitated Capacitor (IDC). A digital readout circuit has been proposed to measure the time-period difference between the two oscillators loaded with samples of healthy and (potentially) unhealthy blood. A prototype circuit was designed in 65-nm CMOS technology and post-layout simulations show 15.25-aF sensitivity. The total circuit occupies 2,184-[Formula: see text]m2 silicon area and consumes 216[Formula: see text][Formula: see text]A from a 1-V power supply.

Publisher

World Scientific Pub Co Pte Lt

Subject

Electrical and Electronic Engineering,Hardware and Architecture,Electrical and Electronic Engineering,Hardware and Architecture

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