STEINER POINTS IN THE SPACE OF GENOME REARRANGEMENTS-Reference-Cited by-同舟云学术

STEINER POINTS IN THE SPACE OF GENOME REARRANGEMENTS

Published:1996-03 Issue:01 Volume:07 Page:1-9
ISSN:0129-0541
Container-title:International Journal of Foundations of Computer Science
language:en
Short-container-title:Int. J. Found. Comput. Sci.

Author:

SANKOFF DAVID¹,SUNDARAM GOPALAKRISHNAN²,KECECIOGLU JOHN³

Affiliation:

1. Centre de recherches mathématiques, Université de Montréal, CP 6128 succursale Centre-Ville, Montréal, Québec, H3C 3J7, Canada

2. Environmental Systems Research Institute, Redlands, CA 92373, USA

3. Department of Computer Science, University of Georgia, Athens, GA 30602, Greece

Abstract

We present some experiences with the problem of multiple genome comparison, analogous to multiple sequence alignment in sequence comparison, under the inversion and transposition distance metrics, given a fixed phylogeny. We first describe a heuristic for the case in which phylogeny is a star on three vertices and then use this to approximate the multiple genome comparison problem via local search.

Publisher

World Scientific Pub Co Pte Lt

Subject

Computer Science (miscellaneous)

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0129054196000026

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