SCALING EFFECTS IN THE PENNA AGEING MODEL

Author:

ŁASZKIEWICZ A.1,CEBRAT S.1,STAUFFER D.2

Affiliation:

1. Department of Genomics, Institute of Genetics and Microbiology, University of Wrocław, ul. Przybyszewskiego 63/77, PL-54148 Wrocław, Poland

2. Institute for Theoretical Physics, Cologne University, D-50923 Köln, Germany

Abstract

We have analyzed the possibility of scaling the sexual Penna ageing model. Assuming that the number of genes expressed before the reproduction age grows linearly with the genome size and that the mutation rate per genome and generation is constant, we have found that the fraction of defective genes expressed before the minimum reproduction age drops with the genome size, while the number of defective genes eliminated by the genetic death grows with genome size. Thus, the evolutionary costs decrease with increasing genome size. After rescaling the time scale according to the mutational clock, age distributions of populations do not depend on the genome size. Nevertheless, enlarging the genome increases the reproduction potential of populations.

Publisher

World Scientific Pub Co Pte Lt

Subject

Control and Systems Engineering

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Mortality curves using a bit-string aging model;Physica A: Statistical Mechanics and its Applications;2020-12

2. PHASE TRANSITION IN THE GENOME EVOLUTION FAVORS NONRANDOM DISTRIBUTION OF GENES ON CHROMOSOMES;International Journal of Modern Physics C;2009-08

3. The Penna Model of Biological Aging;Bioinformatics and Biology Insights;2007-01

4. Anomalies and the Eve effect in the asexual Penna model;Physical Review E;2006-11-21

5. MONTE CARLO SIMULATIONS OF THE INSIDE INTRON RECOMBINATION;International Journal of Modern Physics C;2006-02

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