SUBSTEPS OF KINESIN STUDIED WITH A NECK LINKER SWING MODEL-Reference-Cited by-同舟云学术

SUBSTEPS OF KINESIN STUDIED WITH A NECK LINKER SWING MODEL

Published:2010-03-10 Issue:06 Volume:24 Page:539-548
ISSN:0217-9849
Container-title:Modern Physics Letters B
language:en
Short-container-title:Mod. Phys. Lett. B

Author:

SHU YAO-GEN¹,LI MING²

Affiliation:

1. Key Laboratory of Frontiers in Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100190, China

2. College of Physical Science, Graduate University of Chinese Academy of Sciences, Beijing 100190, China

Abstract

We have proposed the neck linker swing model to investigate the substeps of kinesin. The Michaelis–Menten-like curve for velocity versus ATP concentration at different loads has been obtained, which is in agreement with experiments. We have predicted that the Michaelis constant does not increase monotonically and an elastic instability will happen with increasing applied force.

Publisher

World Scientific Pub Co Pte Lt

Subject

Condensed Matter Physics,Statistical and Nonlinear Physics

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0217984910022597

Reference44 articles.

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2. Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

3. Bead movement by single kinesin molecules studied with optical tweezers

4. Direct observation of kinesin stepping by optical trapping interferometry

5. The Movement of Kinesin Along Microtubules

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