CATANIONIC SUGAR DERIVED AMPHIPHILES: FROM MOLECULES TO TARGETED BIOMIMETIC SYSTEMS

Author:

RICO-LATTES ISABELLE1,BLANZAT MURIEL1,PEREZ EMILE1,SOUSSAN ELODIE1,STEFANIU CRISTINA1

Affiliation:

1. Laboratoire des IMRCP, UMR CNRS 5623, Université Paul Sabatier, 118 Route de Narbonne, 31062 Toulouse Cedex 4, France

Abstract

In the course of our investigations of routes for general and convenient synthesis of amphiphiles derived from sugars, we reported new synthetic ways to prepare catanionic surfactants, polymers and dendrimers using unprotected lactose or lactobionic acid. Moreover we developed amphiphilic dendrimers bearing sugar polar heads. These compounds are of interest for their biological applications (mimics of natural ligands of proteins (e.g. gp 120 of HIV), encapsulation, vectorisation).

Publisher

World Scientific Pub Co Pte Lt

Subject

Molecular Biology,Structural Biology,Biophysics

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