1. Department of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan, R.O.C
2. Department of Surgery, Mackay Memorial Hospital and Mackay Medical College, Taipei 10449, Taiwan, R.O.C
3. Mackay Junior College of Medicine, Nursing and Management, New Taipei City 252, Taiwan, R.O.C
4. Department of Internal Medicine, Kuang-Tien General Hospital, Taichung City 433, Taiwan, R.O.C