Taraxacum: A Review of Ethnopharmacology, Phytochemistry and Pharmacological Activity

Author:

Hao Fusheng1ORCID,Deng Xinxin2ORCID,Yu Xin13ORCID,Wang Wen1ORCID,Yan Wei1ORCID,Zhao Xi1ORCID,Wang Xiaofei1ORCID,Bai Changcai13ORCID,Wang Zhizhong13ORCID,Han Lu13ORCID

Affiliation:

1. School of Pharmacy, Ningxia Medical University, Yinchuan 750004, P. R. China

2. Department of Integration of Chinese and Western Medicine, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Peking University Cancer Hospital & Institute, Beijing 100142, P. R. China

3. Key Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan 750004, P. R. China

Abstract

Taraxacum refers to the genus Taraxacum, which has a long history of use as a medicinal plant and is widely distributed around the world. There are over 2500 species in the genus Taraxacum recorded as medicinal plants in China, Central Asia, Europe, and the Americas. It has traditionally been used for detoxification, diuresis, liver protection, the treatment of various inflammations, antimicrobial properties, and so on. We used the most typically reported Taraxacum officinale as an example and assembled its chemical makeup, including sesquiterpene, triterpene, steroids, flavone, sugar and its derivatives, phenolic acids, fatty acids, and other compounds, which are also the material basis for its pharmacological effects. Pharmacological investigations have revealed that Taraxacum crude extracts and chemical compounds contain antimicrobial infection, anti-inflammatory, antitumor, anti-oxidative, liver protective, and blood sugar and blood lipid management properties. These findings adequately confirm the previously described traditional uses and aid in explaining its therapeutic applications.

Funder

the National Natural Science Foundation of China

Class A, “Western Light” and “Western Young Scholars” of the Chinese Academy of Sciences in 2019

Ningxia Natural Science Foundation

Publisher

World Scientific Pub Co Pte Ltd

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