BIOMECHANICAL OPTIMIZATION OF CO2 ANGIOGRAPHY

Author:

ZANNOLI ROMANO1ORCID,CORAZZA IVAN1ORCID,NERI LUCA23ORCID,CASADEI LORENZO4,MONTI LUCA4

Affiliation:

1. Medical Physics Coordination Centre, Department of Experimental Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Bologna, Italy

2. Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD USA

3. Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy

4. Angiodroid S.r.l, Bologna, Italy

Abstract

Carbon dioxide (CO2) angiography represents an important technique to overcome most clinical problems related to the use of iodine contrast medium. The recent technologic advancements in the fields of gas injection and image reconstructions made CO2 angiography a very efficient method for clinical evaluation of peripheral cardiovascular system. Despite that, some challenges are still open and a better knowledge of the biomechanical behavior of CO2 and its interactions with blood flowing into the vessels is necessary to optimize this technology and to expand its field of application. This paper presents a quick overview about biomechanical behavior of carbon dioxide during injection, suggesting possible optimization tricks to make CO2 angiography procedures more effective to improve imaging and reduce the patients’ radiological dose. Particular attention has been also paid to 3D imaging techniques, which can certainly be opened to the use of carbon dioxide.

Publisher

World Scientific Pub Co Pte Ltd

Subject

Biomedical Engineering

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