MECHANISM OF SENSORINEURAL HEARING LOSS CAUSED BY TYPICAL SCLEROSIS OF COCHLEA-Reference-Cited by-同舟云学术

MECHANISM OF SENSORINEURAL HEARING LOSS CAUSED BY TYPICAL SCLEROSIS OF COCHLEA

Published:2021-12-31 Issue: Volume: Page:
ISSN:0219-5194
Container-title:Journal of Mechanics in Medicine and Biology
language:en
Short-container-title:J. Mech. Med. Biol.

Author:

ZHAO ZHENGSHAN¹²,YAO WENJUAN¹²^ORCID,WANG JIAKUN¹²,ZHOU LEI³^ORCID,HUANG XINSHENG³

Affiliation:

1. School of Mechanics and Engineering Science, Shanghai University, Shanghai 200072, P. R. China

2. Shanghai Institute of Applied Mathematics and Mechanics, Shanghai 200072, P. R. China

3. Otorhinolaryngology-Head and Neck Surgery Department, Zhongshan Hospital Affiliated to Fudan University, Shanghai 200032, P. R. China

Abstract

It is difficult to measure the cochlea directly because of the ethical problems and the complexity of cochlear structure. Therefore, finite element model (FEM) can be used as an effective alternative research method. An accurate FEM of the human ear can not only help people understand the mechanisms of sound transmission, but also effectively assess the effects of otologic diseases and guide research on the treatment of hearing loss. In this paper, a three-dimensional (3D) FEM of the human normal cochlea is proposed to study the changes in the biomechanical behavior of the cochlear sensory structure caused by the anterior fissure sclerosis and bottom-turn and apex-turn ossification of the cochlear window. The degree and harm of hearing loss caused by diseases are quantitatively predicted, which can deepen the understanding of the biomechanical mechanism of cochlea, and provide theoretical basis for clinical medicine.

Funder

Key Programme

Publisher

World Scientific Pub Co Pte Ltd

Subject

Biomedical Engineering

Link

https://www.worldscientific.com/doi/pdf/10.1142/S0219519422500026

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