A NOVEL DEEP LEARNING METHOD FOR BRAIN TUMOR SEGMENTATION IN MAGNETIC RESONANCE IMAGES BASED ON RESIDUAL UNITS AND MODIFIED U-NET MODEL

Author:

CHEN YUXUAN123ORCID,CHEN YUNYI123ORCID,CHEN JIAN2ORCID,HUANG CHENXI23ORCID,WANG BIN1ORCID,CUI XU4ORCID

Affiliation:

1. Emergency Department, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen 361005, P. R. China

2. Fujian Provincial Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, Fuzhou 350122 P. R. China

3. Department of Software Engineering, School of Information, Xiamen University, Xiamen 361005, P. R. China

4. Art College, Xiamen University Xiamen 361005, P. R. China

Abstract

Brain tumors are among the most deadly forms of cancer, as the brain is a crucial organ for human activity. Early detection and treatment are key to recovery. An expert’s final decision on tumor diagnosis mainly depends on the evaluation of Magnetic Resonance Imaging (MRI) images. However, the traditional manual assessment process is time-consuming, error-prone, and relies on the experience and knowledge of doctors, along with other unstable factors. An automated brain tumor detection system can assist radiologists and internal medicine experts in detecting and diagnosing brain tumors. This study proposes a novel deep learning model that combines residual units with a modified U-Net framework for brain tumor segmentation tasks in brain MR images. In this study, the U-Net-based framework is implemented with a stack of neural units and residual units and uses Leaky Rectified Linear Unit (LReLU) as the model’s activation function. First, neural units are added before the first layer of downsampling and upsampling to enhance feature propagation and reuse. Then, the stacking of residual blocks is applied to achieve deep semantic information extraction for downsampling and pixel classification for upsampling. Finally, a single-layer convolution outputs the predicted segmented images. The experimental results show that the segmentation Dice Similarity Coefficient of this model is 90.79%, and the model demonstrates better segmentation accuracy than other research models.

Funder

Open fund of Fujian Provincial Key Laboratory of Molecular Neurology

Open fund of Key Laboratory of Embedded System and Service Computing

China Fundamental Research Funds for the Central Universities

Chinese National Natural Science Foundation

Publisher

World Scientific Pub Co Pte Ltd

Subject

Biomedical Engineering

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